Case Challenge #11 presented a 71 year old gentleman with lethargy, weight loss, and widespread lymphadenopathy with no palpable organomegaly. He has a polyclonal gammopathy and the following biopsy findings:
The correct answer is:
- Symptoms: serious infections, fevers, weight loss, fatigue, night sweats, and nerve damage that can cause weakness and numbness.
- Labs: frequently see anemia, hypergammaglobulinemia.
- Acts very much like lymphoma – in fact, about 20% of people with this disease eventually develop lymphoma.
- Treatment may involve steroids, surgery, chemotherapy or even radiation therapy.
Thanks for playing, case challenge #12 will be posted next week!