Below are some key points regarding bronchiectasis:
- Damage to the airways causing them to widen and become scarred. This causes impaired clearance of mucous resulting in buildup and recurrent lung infections.
- Congenital etiologies (cystic fibrosis, primary ciliary dyskinesia, alpha-1 antitrypsin deficiency) versus acquired (post-infection, idiopathic, aspiration, immunodeficiency, auto-immune, ABPA).
- Patients presents with chronic cough and sputum production. Affects women more than men.
- Typically diagnosed by high resolution CT scan.
- At risk for chronic colonization by Pseudomonas.
- Typical infectious organisms include H. influenzae, Pseudomonas, Moraxella catarrhalis, Mycobacterium, Staph.
- Treatment: Treat underlying condition, antimicrobrial therapy, surgical resection, lung transplant for end stage disease.
O’Donnell. CHEST. 2008.