The Annals of Internal Medicine recently published a report profiling the first 2 domestic cases of Ebola in the United States. Before 2014, only 4 patients with Ebola had been treated in the US, all of them diagnosed in western Africa and evacuated for care. The article details the clinical course of the 45 year-old Liberian male and 26 year-old critical care nurse presenting to Dallas Presbyterian in September 2014. It does an excellent job scientifically depicting illness trajectory and management. An accurate understanding of the Ebola cases in Dallas is essential to improving our country’s response to future outbreaks.