Friday, December 19th
Housestaff vs Faculty
Starting at noon in D 1.520
The faculty took the win last year in a close battle,
but the housestaff are ready to take back the crown!
(hint: read the blog)
There are several trials that explore additional options for the treatment of hepatic encephalopathy. Earlier this month, UT Southwestern researchers (including Dr. Amit Singal, Dr. Jennifer Cuthbert, and other former members of our division of Gastroenterology and Hepatology) published the results of The HELP Randomized Clinical Trial, which compared lactulose to polyethylene glycol (AKA miralax, or golytely!) for the treatment of HE. They concluded that “PEG led to more rapid HE resolution than standard therapy, suggesting that PEG may be superior to standard lactulose therapy in patients with cirrhosis hospitalized for acute HE.” Check out the article at JAMA Internal Medicine.
AMA Intern Med. 2014;174(11):1727-1733. doi:10.1001/jamainternmed.2014.4746.
From the International Journal of Hepatology, here is a more extensive review of the pathophysiology, diagnosis, and treatment of HE.
Z. Poh and P. E. J. Chang, “A Current Review of the Diagnostic and Treatment Strategies of Hepatic Encephalopathy,” International Journal of Hepatology, vol. 2012, Article ID 480309, 10 pages, 2012. doi:10.1155/2012/480309